A chemical, biological, radiological, and nuclear (CBRN) event, irrespective of origin, can cause significant loss of life, and affect public health and the environment (acutely and chronically). The origin of the risk can be intentional (proliferation, theft, sabotage and illicit trafficking), accidental (industrial catastrophes, waste treatment and transport) or natural (mainly pandemics but also be the consequence of natural hazards by CBRN material and facilities). The management of chemicals and waste is a core element of international CBRN safety and security agendas. Chemical production, use and disposal continue to increase worldwde.